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Thyroid / Endocrine Clinical Trials

With an emphasis on transdisciplinary translational research, the OSUCCC-James facilitates investigator-initiated early phase clinical trials and participates in many cooperative groups.
Protocol No.PITitle
OSU-9812Albert de la ChapelleA Strategy to Search for Genes Predisposing to Papillary Carcinoma of the Thyroid When Mutated
OSU-05034Richard KloosRetrospective Clinicopathological Review & Analysis of Benign Thyroid and Thyroid Cancers Cases from the Ohio State University Medical Center to Determine Factors Influencing Diagnosis, Treatment and Long Term Outcome.
OSU-06032Richard KloosThe Endocrine Neoplasia Repository (ENR).
OSU-11126Richard KloosSalivary gland damage and dysfunction in patients with differentiated thyroid cancer treated with radioactive iodine.
OSU-12154Manisha ShahPhase II Study of Cabozantinib in Patients with Radioiodine-Refractory Differentiated Thyroid Cancer Who Progressed on First-Line VEGFR-Targeted Therapy
OSU-12153Manisha ShahA multicenter, two stage, phase II study, evaluating the efficacy of oral BEZ235 plus best supportive care (BSC)versus placebo plus BSC in the treatment of patients with advanced pancreatic neuroendocrine tumors (pNET) after failure of mTOR inhibitor therapy.
OSU-07080Manisha ShahA Banking Facility for Biological Samples and Clinical Data to Study Neuroendocrine Tumors