Neuro-Oncology Clinical Trials
Page Introduction
With an emphasis on transdisciplinary translational research, the
OSUCCC-James facilitates investigator-initiated early phase clinical
trials and participates in many cooperative groups.
| Protocol No. | PI | Title |
|---|
| ECOG-E3F05 | Robert Cavaliere | Phase III Study of Radiation Therapy with or without Temozolomide for Symptomatic or Progressive Low-Grade Gliomas |
| RTOG-0929 | Robert Cavaliere | A Randomized Phase I/II Study of ABT-888 in Combination with Temozolomide in Recurrent (Temozolomide Resistant) Glioblastoma. |
| OSU-13094 | Robert Cavaliere | HSPPC-96 Expanded Access (Compassionate Use) Treatment Protocol for an individual Patient |
| OSU-12105 | James Elder | A Continuation Protocol for Patients Previously Enrolled in a Study of Toca 511 |
| OSU-10151 | James Elder | Intracerebral convection enhanced delivery of carboplatin for treatment of recurrent high-grade gliomas |
| OSU-11122 | James Elder | A Phase 1 Ascending Dose Trial of the Safety and Tolerability of Toca 511, a Retroviral Replicating Vector, Administered to Subjects at the Time of Resection for Recurrent High Grade Glioma and Followed by Treatment with Toca FC, Extended-Release 5-FC |
| OSU-10130 | James Elder | NIH 1308: The Cancer Genome Atlas Patient Enrollment and Specimen Qualification Criteria Grade II-IV Gliomas |
| OSU-07147 | James Elder | Ohio Brain Tumor Study (OBTS) |
| OSU-08142 | John Grecula | Phase I Study of Bendamustine and Fractionated Stereotactic Radiotherapy of Patients with 1- 4 Brain Metastases from Solid Malignancies |
| OSU-05094 | Sean Lawler | Investigating Novel Therapeutic Strategies for Brain Tumor Treatment. |
| OSU-08118 | Ehud Mendel | Functional Outcome in Patients Following Surgical Decompression and Stabilization for Spinal Metastases: Surgical Impact and Quality of Life |
| OSU-12079 | Herbert Newton | An International, Randomized, Double-Blind, Controlled Study of
Rindopepimut/GMCSF with Adjuvant Temozolomide in Patients with Newly Diagnosed, Surgically Resected, EGFRvIII-positive Glioblastoma |
| OSU-12094 | Herbert Newton | A Prospective, Multi-center Trial of NovoT T F-100A Together With Temozolomide Compared to Temozolomide Alone in Patients with Newly Diagnosed GBM |
| RTOG-0631 | Christopher Pelloski | Phase II/III Study of Image-Guided Radiosurgery/SBRT for Localized Spine Metastasis |
| OSU-05092 | James Van Brocklyn | The Role Shingosine Kinase in Astrocytic Gliomas. |
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