Alison Walker R. MD

Alison Walker R. MD
Asst ProfessorCollege of Medicinewalker.1088@osu.edu
Starling Loving Hall 320 W 10th Avenue Columbus Ohio 43210
Phone:614-293-9869Fax: (614) 293-7526
  • Leukemia Research

Research Description

Dr. Walker's research interests are in AML and MDS(Acute Myeloid Leukemia and Myelodysplastic Syndromes)

Current Publications

  • Walker AR, Klisovic RB, Garzon R, Schaaf LJ, Humphries K, Devine SM, Byrd JC, Grever MR, Marcucci G, Blum WPhase I study of azacitidine and bortezomib in adults with relapsed or refractory acute myeloid leukemia.Leuk Lymphoma 55 1304-8 6/1/2014
  • Walker AR, Marcucci GManagement of patients with cytogenetically normal acute myeloid leukemia who have neither favorable nor unfavorable markers.J Natl Compr Canc Netw 12 527-34 4/1/2014
  • Walker A, Becker MW, Ifthikharuddin JJ, Mulford D, Chen R, Bechelli J, Rosell K, Minhajuddin M, Jordan CT, Phillips GL, Liesveld JL, O'Dwyer KA phase I study of decitabine and rapamycin in relapsed/refractory AML.Leuk Res 37 1622-7 12/1/2013
  • Walker AR, Klisovic R, Johnston JS, Jiang Y, Geyer S, Kefauver C, Binkley P, Byrd JC, Grever MR, Garzon R, Phelps MA, Marcucci G, Blum KA, Blum WPharmacokinetics and dose escalation of the heat shock protein inhibitor 17-allyamino-17-demethoxygeldanamycin in combination with bortezomib in relapsed or refractory acute myeloid leukemia.Leuk Lymphoma 54 1996-2002 9/1/2013
  • Bloomfield CD, Caligiuri MA, Lee RJ, Garzon R, Muthusamy N, Lee LJ, Marcucci G, Huang X, Schwind S, Yu B, Santhanam R, Wang H, Hoellerbauer P, Mims A, Klisovic R, Walker AR, Chan KK, Blum W, Perrotti D, Byrd JCTargeted delivery of microRNA-29b by transferrin-conjugated anionic lipopolyplex nanoparticles: a novel therapeutic strategy in acute myeloid leukemia.Clin Cancer Res 19 2355-67 5/1/2013
  • Walker A, Mrózek K, Kohlschmidt J, Rao KW, Pettenati MJ, Sterling LJ, Marcucci G, Carroll AJ, Bloomfield CD, Alliance for Clinical Trials in OncologyNew recurrent balanced translocations in acute myeloid leukemia and myelodysplastic syndromes: cancer and leukemia group B 8461.Genes Chromosomes Cancer 52 385-401 4/1/2013
  • Mims A, Walker AR, Garzon R, Schwind S, Marcucci G, Huang X, Sun J, Wang H, Santhanam R, Dorrance AM, Walker C, Hoellerbauer P, Tarighat SS, Chan KK, Klisovic RB, Perrotti D, Caligiuri MA, Byrd JC, Chen CS, James Lee L, Jacob S, Mrózek K, Bloomfield CD, Blum WIncreased anti-leukemic activity of decitabine via AR-42-induced upregulation of miR-29b: a novel epigenetic-targeting approach in acute myeloid leukemia.Leukemia 27 871-8 4/1/2013
  • Wu YZ, Alachkar H, Maharry K, Nicolet D, Mrózek K, Walker A, Eiring AM, Whitman SP, Becker H, Perrotti D, Wu LC, Zhao X, Fehniger TA, Vij R, Byrd JC, Blum W, Lee LJ, Caligiuri MA, Bloomfield CD, Garzon R, Marcucci G, Hickey CJ, Schwind S, Radomska HS, Dorrance AM, Santhanam R, Mishra ALenalidomide-mediated enhanced translation of C/EBPα-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia.Blood 121 159-69 1/3/2013
  • Klisovic R, Walker A, Garzon R, Blum W, Chan KK, Marcucci G, Wang H, Chen P, Wang J, Santhanam R, Aimiuwu J, Saradhi UV, Liu Z, Schwind S, Mims A, Byrd JC, Grever MR, Villalona-Calero MAIn vivo quantification of active decitabine-triphosphate metabolite: a novel pharmacoanalytical endpoint for optimization of hypomethylating therapy in acute myeloid leukemia.AAPS J 15 242-9 1/1/2013
  • Racke F, Cole C, Walker A, Jones J, Heerema NATherapy-related pro-B cell acute lymphoblastic leukemia: report of two patients with MLL amplification.Cancer Genet 205 653-6 12/1/2012
  • Tallman MS, Damon LE, Walker AR, Marcucci G, Sholi AM, Morris GJ, Baikaidi M, Chung SSA 75-year-old woman with thoracic spinal cord compression and chloroma (granulocytic sarcoma).Semin Oncol 39 e37-46 12/1/2012
  • Walker A, Marcucci GMolecular prognostic factors in cytogenetically normal acute myeloid leukemia.Expert Rev Hematol 5 547-58 10/1/2012
  • Yan P, Frankhouser D, Murphy M, Tam HH, Rodriguez B, Curfman J, Trimarchi M, Geyer S, Wu YZ, Whitman SP, Metzeler K, Walker A, Klisovic R, Jacob S, Grever MR, Byrd JC, Bloomfield CD, Garzon R, Blum W, Caligiuri MA, Bundschuh R, Marcucci GGenome-wide methylation profiling in decitabine-treated patients with acute myeloid leukemia.Blood 120 2466-74 9/20/2012
  • Ranganathan P, Yu X, Na C, Santhanam R, Shacham S, Kauffman M, Walker A, Klisovic R, Blum W, Caligiuri M, Croce CM, Marcucci G, Garzon RPreclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia.Blood 120 1765-73 8/30/2012

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu