Dennis Bong PhD

Dennis Bong PhD
Assoc ProfessorArts and Sciencesbong.6@osu.eduwebsite
3050 Evans Laboratory 88 W 18th Avenue Columbus Ohio 43210
Phone:614-247-8404Fax:
  • Non-Member

Research Description

Our research program is focussed on both the fundamental and applied aspects of organic chemistry at interfaces, particularly lipid membranes. We are pursuing new tools to illuminate lipid membrane biophysics and for controlled chemical delivery to living cells and tissues. Membrane transformations are used in Nature to control the release of chemical agents to designated in vivo targets; we seek to design synthetic lipid and polymer systems that will deliver chemical cargo in a similarly selective manner, predicated on an understanding of lipid assembly biophysics. Research in the group is highly multidisciplinary: projects begins with organic synthesis and branch into biophysics, bioanalytical studies and cell biology. Researchers with these diverse backgrounds work together to investigate interfacial molecular recognition and its applications in biotechnology and materials science. To this end, our group pursues research in the design and organic synthesis of simple but potentially biologically interesting lipids, peptides, polymers and membrane assemblies.

Current Publications

  • Bong D, Xia X, Piao X, Fredrick KBifacial PNA complexation inhibits enzymatic access to DNA and RNA.Chembiochem 15 31-6 1/3/2014
  • Zhou Z, Bong DSmall-molecule/polymer recognition triggers aqueous-phase assembly and encapsulation.Langmuir 29 144-50 1/8/2013

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu