M. Guillaume Wientjes PhD

M. Guillaume Wientjes PhD
Faculty EmeritusCollege of Pharmacywientjes.1@osu.edu
512 Riffe Building 496 W 12th Avenue Columbus Ohio 43210
Phone:614-292-6488Fax: (614) 292-4055
  • Translational Therapeutics

Research Description

Dr. Wientjes’ research interests include pharmacodynamics of drugs for prostate and pancreatic cancer and pharmacokinetic approaches to understand and improve regional cancer therapy, polymer-based slow release systems for regional drug administration, and mathematical modeling of biological processes.

Current Publications

  • Gan Y, Lu J, Yeung BZ, Cottage CT, Wientjes MG, Au JLPharmacodynamics of Telomerase Inhibition and Telomere Shortening by Noncytotoxic Suramin.AAPS J in press 11/26/2014
  • Au JL, Guo P, Gao Y, Lu Z, Wientjes MG, Tsai M, Wientjes MGMultiscale tumor spatiokinetic model for intraperitoneal therapy.AAPS J 16 424-39 5/1/2014
  • Wang J, Lu Z, Yeung BZ, Wientjes MG, Cole DJ, Au JLTumor priming enhances siRNA delivery and transfection in intraperitoneal tumors.J Control Release 178 79-85 3/28/2014
  • Lu Z, Tsai M, Wang J, Cole DJ, Wientjes MG, Au JLActivity of drug-loaded tumor-penetrating microparticles in peritoneal pancreatic tumors.Curr Cancer Drug Targets 14 70-8 1/1/2014
  • Alvarez FJ, Kisseberth W, Hosoya K, Lara-Garcia A, Kosarek C, Murahari S, Au JL, Wientjes MG, Couto J, Couto GPostoperative adjuvant combination therapy with doxorubicin and noncytotoxic suramin in dogs with appendicular osteosarcoma.J Am Anim Hosp Assoc 50 12-8 1/1/2014
  • Tsai M, Lu Z, Wientjes MG, Au JLPaclitaxel-loaded polymeric microparticles: quantitative relationships between in vitro drug release rate and in vivo pharmacodynamics.J Control Release 172 737-44 12/28/2013
  • Gao Y, Li M, Chen B, Shen Z, Guo P, Wientjes MG, Au JLPredictive models of diffusive nanoparticle transport in 3-dimensional tumor cell spheroids.AAPS J 15 816-31 7/1/2013

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 460 W. 10th Avenue, Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu