Sameek Roychowdhury MD, PhD

Sameek Roychowdhury MD, PhD
Asst ProfessorCollege of Medicineroychowdhury.1@osu.eduwebsite
508 Graves Hall 460 W 12th Avenue Columbus Ohio 43210
Phone:614-685-5842Fax: (614) 292-6356
  • Translational Therapeutics

Research Description

Dr. Roychowdhury is a physician scientist in medical oncology focusing on translational cancer genomics and implementing precision cancer medicine. His clinical practice in medical oncology includes patients with advanced, metastatic cancer including prostate, colorectal, and rare cancer subtypes. The overarching goals of the lab include 1) utilizing genomic testing strategies for patients with advanced cancer, 2) identifying the right drug(s) and trials for patients with advanced cancer using genomic testing, 3) identification and study of predictive genomic biomarkers for targeted therapies, 4) genomics or mutation-based clinical trials, and 5) elucidating primary and secondary resistance mechanisms for targeted therapies. This includes a CLIA grade Cancer Genomics Laboratory for validated and targeted genomic assays and research grade, discovery whole exome/RNA sequencing.

Current Publications

  • Roy A, Plon SE, Roychowdhury S, Chinnaiyan AM, Parsons DWClinical tumor sequencing: an incidental casualty of the american college of medical genetics and genomics recommendations for reporting of incidental findings.J Clin Oncol 32 2203-5 7/20/2014
  • Robinson DR, Wu YM, Vats P, Su F, Lonigro RJ, Cao X, Kalyana-Sundaram S, Wang R, Ning Y, Hodges L, Gursky A, Siddiqui J, Tomlins SA, Roychowdhury S, Pienta KJ, Kim SY, Roberts JS, Rae JM, Van Poznak CH, Hayes DF, Chugh R, Kunju LP, Talpaz M, Schott AF, Chinnaiyan AMActivating ESR1 mutations in hormone-resistant metastatic breast cancer.Nat Genet 45 1446-51 12/1/2013
  • Feng FY, Zalupski MM, Talpaz M, Pienta KJ, Rhodes DR, Robinson DR, Chinnaiyan AM, Wu YM, Su F, Kalyana-Sundaram S, Khazanov N, Ateeq B, Cao X, Lonigro RJ, Vats P, Wang R, Lin SF, Cheng AJ, Kunju LP, Siddiqui J, Tomlins SA, Wyngaard P, Sadis S, Roychowdhury S, Hussain MHIdentification of targetable FGFR gene fusions in diverse cancers.Cancer Discov 3 636-47 6/1/2013
  • Roychowdhury S, Chinnaiyan AMAdvancing precision medicine for prostate cancer through genomics.J Clin Oncol 31 1866-73 5/20/2013
  • Simon R, Roychowdhury SImplementing personalized cancer genomics in clinical trials.Nat Rev Drug Discov 12 358-69 5/1/2013

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu