Vincenzo Coppola MD


Vincenzo Coppola MD
Asst ProfessorCollege of Medicinecoppola.20@osu.edu
988 Biomedical Research Tower 460 W 12th Avenue Columbus Ohio 43210
Phone:614-688-8038Fax: 614-688-5933
  • Molecular Biology and Cancer Genetics

Research Description

Dr. Coppola’s expertise is to generate genetically modified mouse models to mimic human diseases and study gene functions in vivo. He is also interested in clarifying the role of neurotrophins (NTs) and their receptors (Trks) in vivo using specific mouse models.

Current Publications

  • Gopinathan L, Tan SL, Padmakumar VC, Coppola V, Tessarollo L, Kaldis PLoss of cdk2 and cyclin A2 impairs cell proliferation and tumorigenesis.Cancer Res 74 3870-9 7/15/2014
  • Kiris E, Wang T, Yanpallewar S, Dorsey SG, Becker J, Bavari S, Palko ME, Coppola V, Tessarollo LTrkA in vivo function is negatively regulated by ubiquitination.J Neurosci 34 4090-8 3/12/2014
  • Hodge DL, Berthet C, Coppola V, Kastenmüller W, Buschman MD, Schaughency PM, Shirota H, Scarzello AJ, Subleski JJ, Anver MR, Ortaldo JR, Lin F, Reynolds DA, Sanford ME, Kaldis P, Tessarollo L, Klinman DM, Young HAIFN-gamma AU-rich element removal promotes chronic IFN-gamma expression and autoimmunity in mice.J Autoimmun in press 2/28/2014
  • Efanov A, Zanesi N, Coppola V, Nuovo G, Bolon B, Wernicle-Jameson D, Lagana A, Hansjuerg A, Pichiorri F, Croce CMHuman HMGA2 protein overexpressed in mice induces precursor T-cell lymphoblastic leukemia.Blood Cancer J 4 e227 1/1/2014
  • Pichiorri F, Palmieri D, De Luca L, Consiglio J, You J, Rocci A, Talabere T, Piovan C, Lagana A, Cascione L, Guan J, Gasparini P, Balatti V, Nuovo G, Coppola V, Hofmeister CC, Marcucci G, Byrd JC, Volinia S, Shapiro CL, Freitas MA, Croce CMIn vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation.J Exp Med 210 951-68 5/6/2013
  • Balamurugan K, Sharan S, Klarmann KD, Zhang Y, Coppola V, Summers GH, Roger T, Morrison DK, Keller JR, Sterneck EFBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4.Nat Commun 4 1662 1/1/2013

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu