Victor Jin X. PhD


Victor Jin X. PhD
Asst ProfessorCollege of MedicineVictor.Jin@osumc.edu
3190 Graves Hall 333 W 10th Avenue Columbus OH 43210
Phone:(614) 292-6931Fax: (314) 688-6600
  • Non-Member

Research Description

My research focuses include building computational models in order to understand the mechanism of cancer cells and identify the functional elements in genome sequences, performing cluster analysis in order to recognize gene expression patterns, as well as consultation with scientists on experimental design and data collection, analysis of biological data for cancer research projects by adopting new methodologies. One of my major achievements in this research field is that I am the leading author to develop a computational genomics approach to discover regulatory modules in cancer cells and further to decipher the logic of regulatory networks in cancers, where the results were published on Genome Research, 16, 1585-1595 (2006), 17, 807-817 (2007), Molecular Cell 21, 393-404 (2006), Cancer Research 68, 9654-9662 (2008), 64, 8184-8192 (2004), Nucleic Acids Research 32, 6627-6635 (2004) and Journal of Molecular Endocrinology 35, 225-230 (2005).

Current Publications

  • Bonneville R, Jin VXA hidden Markov model to identify combinatorial epigenetic regulation patterns for estrogen receptor α target genes.Bioinformatics 29 22-8 1/1/2013
  • Blattler A, Yao L, Wang Y, Ye Z, Jin VX, Farnham PJZBTB33 binds unmethylated regions of the genome associated with actively expressed genes.Epigenetics Chromatin 6 13 1/1/2013
  • Miuma S, Saldivar JC, Karras JR, Waters CE, Paisie CA, Wang Y, Jin V, Sun J, Druck T, Zhang J, Huebner KFhit deficiency-induced global genome instability promotes mutation and clonal expansion.PLoS One 8 e80730 1/1/2013
  • Wang J, Lan X, Hsu PY, Hsu HK, Huang K, Parvin J, Huang TH, Jin VXGenome-wide analysis uncovers high frequency, strong differential chromosomal interactions and their associated epigenetic patterns in E2-mediated gene regulation.BMC Genomics 14 70 1/1/2013
  • Liu B, Yi J, Sv A, Lan X, Ma Y, Huang TH, Leone G, Jin VXQChIPat: a quantitative method to identify distinct binding patterns for two biological ChIP-seq samples in different experimental conditions.BMC Genomics 14 Suppl 8 S3 1/1/2013
  • Wang R, Hsu HK, Blattler A, Wang Y, Lan X, Wang Y, Hsu PY, Leu YW, Huang TH, Farnham PJ, Jin VXLOcating non-unique matched tags (LONUT) to improve the detection of the enriched regions for ChIP-seq data.PLoS One 8 e67788 1/1/2013
  • Jiao H, Hoag K, Wen B, Srinivas M, Waidyaratne G, Wang R, Wojcicka A, Lattimer IR, Stachlewska E, Czetwertynska M, Dlugosinska J, Gierlikowski W, Ploski R, Krawczyk M, Jazdzewski K, Kere J, Symer DE, Jin V, Wang Q, de la Chapelle A, He H, Li W, Wu D, Nagy R, Liyanarachchi S, Akagi K, Jendrzejewski JUltra-rare mutation in long-range enhancer predisposes to thyroid carcinoma with high penetrance.PLoS One 8 e61920 1/1/2013
  • Duran C, Comstock G, Trikha P, Mair M, Senapati S, Martin CK, Gandhi S, Wilson N, Liu B, Huang YW, Thompson JC, Raman S, Singh S, Leone M, Machiraju R, Huang K, Mo X, Fernandez S, Kalaszczynska I, Wolgemuth DJ, Sicinski P, Huang T, Jin V, Leone G, Chen HZ, Ouseph MM, Li J, Pécot T, Chokshi V, Kent L, Bae S, Byrne MCanonical and atypical E2Fs regulate the mammalian endocycle.Nat Cell Biol 14 1192-202 11/1/2012
  • Lan X, Farnham PJ, Jin VXUncovering transcription factor modules using one- and three-dimensional analyses.J Biol Chem 287 30914-21 9/7/2012
  • Lan X, Witt H, Katsumura K, Ye Z, Wang Q, Bresnick EH, Farnham PJ, Jin VXIntegration of Hi-C and ChIP-seq data reveals distinct types of chromatin linkages.Nucleic Acids Res 40 7690-704 9/1/2012

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu