Patrick Nana-Sinkam MD


Patrick Nana-Sinkam MD
Assoc ProfessorCollege of Medicinenana-sinkam.1@osu.edu
201 Davis Heart & Lung Research Inst 473 W 12th Avenue Columbus Ohio 43210
Phone:614-293-4925Fax:
  • Molecular Biology and Cancer Genetics

Current Publications

  • Wu Y, Kwak KJ, Agarwal K, Marras A, Wang C, Mao Y, Huang X, Ma J, Yu B, Lee RJ, Vachani A, Marcucci G, Byrd JC, Muthusamy N, Otterson G, Huang K, Castro CE, Paulaitis ME, Nana-Sinkam SP, Lee LJDetection of Extracellular RNAs in Cancer and Viral Infection via Tethered Cationic Lipoplex Nanoparticles Containing Molecular Beacons.Anal Chem 85 11265-74 12/3/2013
  • Peng Y, Dai Y, Hitchcock C, Yang X, Kassis ES, Liu L, Luo Z, Sun HL, Cui R, Wei H, Kim T, Lee TJ, Jeon YJ, Nuovo GJ, Volinia S, He Q, Yu J, Nana-Sinkam P, Croce CMInsulin growth factor signaling is regulated by microRNA-486, an underexpressed microRNA in lung cancer.Proc Natl Acad Sci U S A 110(37) 15043-8 9/10/2013
  • Powell CA, Halmos B, Nana-Sinkam SPUpdate in lung cancer and mesothelioma 2012.Am J Respir Crit Care Med 188(2) 157-66 7/15/2013
  • Wu Y, Terp MC, Kwak KJ, Gallego-Perez D, Nana-Sinkam SP, Lowrie WG, Lee LJSurface-mediated nucleic acid delivery by lipoplexes prepared in microwell arrays.Small 9(13) 2358-67 7/8/2013
  • Acunzo M, Romano G, Palmieri D, Laganá A, Garofalo M, Balatti V, Drusco A, Chiariello M, Nana-Sinkam P, Croce CMCross-talk between MET and EGFR in non-small cell lung cancer involves miR-27a and Sprouty2.Proc Natl Acad Sci U S A 110(21) 8573-8 5/21/2013
  • Nana-Sinkam SP, Powell CAMolecular biology of lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines.Chest 143(5 Suppl) e30S-9S 5/1/2013
  • Wu Y, Crawford M, Mao Y, Lee RJ, Davis IC, Elton TS, Lee LJ, Nana-Sinkam SPTherapeutic Delivery of MicroRNA-29b by Cationic Lipoplexes for Lung Cancer.Mol Ther Nucleic Acids 2 e84 4/16/2013
  • Dakhlallah D, Batte K, Wang Y, Cantemir-Stone CZ, Yan P, Nuovo G, Mikhail A, Hitchcock CL, Wright VP, Nana-Sinkam P, Piper MG, Marsh CBEpigenetic regulation of miR-17~92 contributes to the pathogenesis of pulmonary fibrosis.Am J Respir Crit Care Med 187(4) 397-405 2/15/2013
  • Kang HW, Crawford M, Fabbri M, Nuovo G, Garofalo M, Nana-Sinkam SP, Friedman AA mathematical model for microRNA in lung cancer.PLoS One 8(1) e53663 1/1/2013
  • Garofalo M, Jeon YJ, Nuovo GJ, Middleton J, Secchiero P, Joshi P, Alder H, Nazaryan N, Di Leva G, Romano G, Crawford M, Nana-Sinkam P, Croce CMMiR-34a/c-Dependent PDGFR-α/β Downregulation Inhibits Tumorigenesis and Enhances TRAIL-Induced Apoptosis in Lung Cancer.PLoS One 8(6) e67581 1/1/2013
  • Nana-Sinkam SP, Croce CMClinical applications for microRNAs in cancer.Clin Pharmacol Ther 93(1) 98-104 1/1/2013
  • Wu Y , Duan W, Otterson GA, Lee L, Nana-Sinkam PResearch Highlight: miRNA and platinum-based chemotherapy response in non-small-cell lung cancerPersonalized Medicine 9 329-32 11/1/2012
  • Fabbri M, Paone A, Calore F, Galli R, Gaudio E, Santhanam R, Lovat F, Fadda P, Mao C, Nuovo GJ, Zanesi N, Crawford M, Ozer GH, Wernicke D, Alder H, Caligiuri MA, Nana-Sinkam P, Perrotti D, Croce CMMicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response.Proc Natl Acad Sci U S A 109(31) E2110-6 7/31/2012

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu