Jun Liu PhD


Jun Liu PhD
Assoc ProfessorCollege of Engineeringliu.314@osu.edu
Room 298 Bevis Hall 1080 Carmack Road Columbus Ohio 43210
Phone:614-247-8904Fax: 614-292-7301
  • Molecular Biology and Cancer Genetics

Research Description

Dr. Liu collaborates with clinicians and medical researchers in pursuing a better understanding of biomechanics in ocular pathophysiology, particularly those related to glaucoma and keratoconus. Her lab applies quantitative ultrasound techniques to non-invasively characterize ocular biomechanics.

Current Publications

  • Palko JR, Tang J, Cruz Perez B, Pan X, Liu JSpatially heterogeneous corneal mechanical responses before and after riboflavin-ultraviolet-A crosslinking.J Cataract Refract Surg 40 1021-31 6/1/2014
  • Metzler KM, Mahmoud AM, Liu J, Roberts CJDeformation response of paired donor corneas to an air puff: intact whole globe versus mounted corneoscleral rim.J Cataract Refract Surg 40 888-96 6/1/2014
  • Cruz Perez B, Tang J, Morris HJ, Palko JR, Pan X, Hart RT, Liu JBiaxial mechanical testing of posterior sclera using high-resolution ultrasound speckle tracking for strain measurements.J Biomech 47 1151-6 3/21/2014
  • Bernot KM, Nemer JS, Santhanam R, Liu S, Zorko NA, Whitman SP, Dickerson KE, Zhang M, Yang X, McConnell KK, Ahmed EH, Muñoz MR, Siebenaler RF, Marcucci GG, Mundy-Bosse BL, Brook DL, Garman S, Dorrance AM, Zhang X, Zhang J, Lee RJ, Blum W, Caligiuri MA, Marcucci GEradicating acute myeloid leukemia in a Mll(PTD/wt):Flt3(ITD/wt) murine model: a path to novel therapeutic approaches for human disease.Blood 122 3778-83 11/28/2013
  • Morris HJ, Tang J, Cruz Perez B, Pan X, Hart RT, Weber PA, Liu JCorrelation between biomechanical responses of posterior sclera and IOP elevations during micro intraocular volume change.Invest Ophthalmol Vis Sci 54 7215-22 11/1/2013
  • Palko JR, Iwabe S, Pan X, Agarwal G, Komáromy AM, Liu JBiomechanical properties and correlation with collagen solubility profile in the posterior sclera of canine eyes with an ADAMTS10 mutation.Invest Ophthalmol Vis Sci 54 2685-95 4/1/2013
  • Yu J, Peng Y, Wu LC, Xie Z, Deng Y, Hughes T, He S, Mo X, Chiu M, Wang QE, He X, Liu S, Grever MR, Chan KK, Liu ZCurcumin down-regulates DNA methyltransferase 1 and plays an anti-leukemic role in acute myeloid leukemia.PLoS One 8 e55934 1/1/2013
  • Mishra A, Liu S, Sams GH, Curphey DP, Santhanam R, Rush LJ, Schaefer D, Falkenberg LG, Sullivan L, Jaroncyk L, Yang X, Fisk H, Wu LC, Hickey C, Chandler JC, Wu YZ, Heerema NA, Chan KK, Perrotti D, Zhang J, Porcu P, Racke FK, Garzon R, Lee RJ, Marcucci G, Caligiuri MAAberrant overexpression of IL-15 initiates large granular lymphocyte leukemia through chromosomal instability and DNA hypermethylation.Cancer Cell 22 645-55 11/13/2012
  • Tang J, Liu JUltrasonic measurement of scleral cross-sectional strains during elevations of intraocular pressure: method validation and initial results in posterior porcine sclera.J Biomech Eng 134 091007 9/1/2012
  • Ritchey ER, Zelinka C, Tang J, Liu J, Code KA, Petersen-Jones S, Fischer AJVision-guided ocular growth in a mutant chicken model with diminished visual acuity.Exp Eye Res 102 59-69 9/1/2012

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu